TRPM2-AS

TRPM2 antisense RNA, the group of Antisense RNAs

Basic information

Region (hg38): 21:44414588-44425272

Links

ENSG00000230061 ∙ NCBI:101928607 ∙ ∙ HGNC:50758 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the TRPM2-AS gene.

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the TRPM2-AS gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			10	1	4	15
Total	0	0	10	1	4

Variants in TRPM2-AS

This is a list of pathogenic ClinVar variants found in the TRPM2-AS region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
21-44417907-T-C			Benign (Jun 19, 2021)
21-44417953-A-C		not specified	Uncertain significance (Jan 05, 2022)
21-44417954-C-G		not specified	Uncertain significance (Nov 07, 2022)
21-44417993-C-G		not specified	Uncertain significance (Jul 07, 2024)
21-44418018-G-A		not specified	Uncertain significance (Oct 20, 2023)
21-44418028-C-G		not specified	Uncertain significance (Mar 07, 2024)
21-44418060-A-C		not specified	Uncertain significance (Mar 16, 2022)
21-44418084-C-T		not specified	Uncertain significance (Aug 01, 2024)
21-44418094-G-C		not specified	Uncertain significance (May 08, 2024)
21-44418501-G-A			Uncertain significance (Mar 20, 2018)
21-44418749-C-T			Benign (Jun 19, 2021)
21-44423740-C-T			Likely benign (Dec 31, 2019)
21-44424718-C-T			Benign (Jun 19, 2021)
21-44424868-A-A			Benign (Dec 31, 2019)
21-44424879-T-C		not specified	Uncertain significance (Jan 24, 2023)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP