TTC28-AS1

TTC28 antisense RNA 1, the group of Antisense RNAs

Basic information

Region (hg38): 22:27919303-28008581

Previous symbols: [ "TTC28AS", "TTC28-AS" ]

Links

ENSG00000235954 ∙ NCBI:284900 ∙ ∙ HGNC:29336 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the TTC28-AS1 gene.

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the TTC28-AS1 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			85	10	4	99
Total	0	0	85	10	4

Variants in TTC28-AS1

This is a list of pathogenic ClinVar variants found in the TTC28-AS1 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
22-27982301-C-T		not specified	Likely benign (Jul 19, 2022)
22-27982306-G-A		not specified	Uncertain significance (Nov 23, 2021)
22-27982324-G-A		not specified	Uncertain significance (Aug 12, 2021)
22-27982348-G-A		not specified	Uncertain significance (Jul 13, 2021)
22-27982363-C-T		TTC28-related disorder	Likely benign (Jul 06, 2018)
22-27982396-G-C		TTC28-related disorder	Benign (Jan 03, 2020)
22-27982470-T-C		TTC28-related disorder	Likely benign (Mar 09, 2020)
22-27982532-G-A		not specified	Uncertain significance (Dec 26, 2023)
22-27982532-G-C		not specified	Uncertain significance (May 15, 2024)
22-27982536-G-C		not specified	Uncertain significance (Jul 09, 2021)
22-27982544-T-C		not specified	Uncertain significance (Jun 04, 2024)
22-27982636-T-C		not specified	Uncertain significance (Sep 26, 2024)
22-27982636-T-G		not specified	Uncertain significance (Aug 16, 2022)
22-27982669-C-G		not specified	Uncertain significance (Oct 03, 2022)
22-27982673-C-T		not specified	Uncertain significance (Nov 21, 2022)
22-27982727-A-G		not specified	Uncertain significance (May 12, 2024)
22-27982729-T-G		not specified	Uncertain significance (Apr 18, 2024)
22-27982736-C-T		not specified	Uncertain significance (Aug 19, 2024)
22-27982792-C-T		not specified	Uncertain significance (Jul 30, 2024)
22-27982797-G-A			Likely benign (Jul 19, 2018)
22-27982850-C-T		not specified	Uncertain significance (Aug 10, 2024)
22-27982851-G-A		TTC28-related disorder	Likely benign (Feb 23, 2019)
22-27982862-G-A		not specified	Uncertain significance (Aug 17, 2021)
22-27982964-G-T		not specified	Uncertain significance (Aug 04, 2022)
22-27983000-T-C		not specified	Uncertain significance (Feb 17, 2024)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP