TTC3-AS1

TTC3 antisense RNA 1, the group of Antisense RNAs

Basic information

Region (hg38): 21:37187666-37193926

Links

ENSG00000228677

∙ ∙ ∙ HGNC:40595 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the TTC3-AS1 gene.

Inborn genetic diseases (4 variants)
not provided (1 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the TTC3-AS1 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			4 clinvar	1 clinvar		5
Total	0	0	4	1	0

Variants in TTC3-AS1

This is a list of pathogenic ClinVar variants found in the TTC3-AS1 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Phenotype	Significance	ClinVar
21-37188523-G-A	not specified	Uncertain significance (Jul 28, 2021)	2368508
21-37188565-C-G		Likely benign (Dec 28, 2017)	773091
21-37191393-C-T	not specified	Uncertain significance (Dec 27, 2022)	2402496
21-37192131-T-G	not specified	Uncertain significance (Jun 10, 2022)	2295085
21-37192152-C-T	not specified	Uncertain significance (Oct 14, 2021)	2380920
21-37192212-C-A	not specified	Uncertain significance (Mar 15, 2024)	3329866

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP