ZBTB24-DT

ZBTB24 divergent transcript, the group of Divergent transcripts

Basic information

Region (hg38): 6:109483243-109506852

Links

ENSG00000223537 ∙ NCBI:105377935 ∙ ∙ HGNC:55872 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the ZBTB24-DT gene.

• Inborn genetic diseases (9 variants)
• not provided (5 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the ZBTB24-DT gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			9		5	14
Total	0	0	9	0	5

Variants in ZBTB24-DT

This is a list of pathogenic ClinVar variants found in the ZBTB24-DT region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
6-109493382-G-T		not specified	Uncertain significance (Nov 09, 2022)
6-109493386-C-A		not specified	Uncertain significance (Sep 01, 2021)
6-109493551-C-T		not specified	Uncertain significance (Nov 03, 2022)
6-109494025-C-T		not specified	Uncertain significance (Oct 02, 2023)
6-109495375-A-C		not specified	Uncertain significance (May 14, 2024)
6-109495381-G-A		not specified	Uncertain significance (Oct 18, 2021)
6-109495427-A-T		not specified	Uncertain significance (Mar 31, 2024)
6-109497503-A-G			Benign (May 09, 2018)
6-109497537-A-G		not specified	Uncertain significance (Mar 15, 2024)
6-109497859-C-T		not specified	Uncertain significance (Aug 21, 2023)
6-109497896-T-G		not specified	Uncertain significance (Feb 05, 2024)
6-109497932-G-A		not specified	Uncertain significance (Feb 02, 2022)
6-109499129-A-G		not specified	Uncertain significance (May 20, 2024)
6-109499186-C-T		not specified	Uncertain significance (Oct 04, 2022)
6-109499194-C-T			Benign (Feb 26, 2018)
6-109499214-A-ATAAC		Spermatogenic failure 89	Pathogenic (Feb 05, 2024)
6-109499227-G-A			Benign (Mar 01, 2023)
6-109499235-C-T		not specified	Uncertain significance (Jun 02, 2023)
6-109506403-C-A			Benign (Oct 09, 2017)
6-109506491-T-C		not specified	Uncertain significance (Dec 17, 2023)
6-109506526-A-G			Benign (Apr 30, 2018)
6-109506531-G-A		not specified	Uncertain significance (Mar 07, 2024)
6-109506743-C-A		not specified	Uncertain significance (Apr 27, 2023)
6-109506757-G-T		not specified	Uncertain significance (May 26, 2024)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP