ZNF341-AS1

ZNF341 antisense RNA 1, the group of Antisense RNAs

Basic information

Region (hg38): 20:33787373-33812321

Links

ENSG00000230753 ∙ NCBI:101929746 ∙ ∙ HGNC:50736 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the ZNF341-AS1 gene.

• not provided (140 variants)
• Inborn genetic diseases (24 variants)
• Hyper-IgE recurrent infection syndrome 3, autosomal recessive (4 variants)
• not specified (2 variants)
• Long QT syndrome (1 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the ZNF341-AS1 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding	1		81	55	12	149
Total	1	0	81	55	12

Variants in ZNF341-AS1

This is a list of pathogenic ClinVar variants found in the ZNF341-AS1 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
20-33788846-G-A			Benign (Jan 22, 2024)
20-33788846-G-C			Likely benign (Aug 18, 2023)
20-33788857-C-T			Likely benign (Nov 13, 2023)
20-33788858-T-C			Benign (Dec 11, 2023)
20-33788867-G-A			Likely benign (Apr 08, 2022)
20-33788870-G-A			Likely benign (Nov 18, 2023)
20-33788887-T-C			Uncertain significance (Dec 12, 2023)
20-33788891-C-T			Likely benign (Sep 22, 2023)
20-33788899-C-T			Uncertain significance (Oct 18, 2022)
20-33788900-G-T			Likely benign (Jan 06, 2022)
20-33788906-C-A		not specified	Uncertain significance (Mar 21, 2023)
20-33788907-C-T			Uncertain significance (Dec 11, 2023)
20-33788913-G-A			Uncertain significance (Aug 21, 2022)
20-33788919-C-T			Likely benign (Dec 26, 2023)
20-33788924-G-A			Likely benign (Jan 12, 2023)
20-33788926-G-A		not specified	Uncertain significance (Dec 11, 2023)
20-33788930-CAT-C			Pathogenic (Mar 12, 2022)
20-33788939-C-T		ZNF341-related disorder	Benign (Feb 01, 2024)
20-33788942-C-T		ZNF341-related disorder	Benign (Jan 31, 2024)
20-33788944-A-G			Uncertain significance (May 06, 2021)
20-33788948-C-T			Likely benign (Sep 01, 2022)
20-33788953-A-G			Uncertain significance (Aug 05, 2022)
20-33788972-C-T			Likely benign (Dec 16, 2023)
20-33788973-T-C			Uncertain significance (Oct 05, 2022)
20-33788974-C-T			Uncertain significance (Apr 25, 2022)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP