DLX6-AS1

DLX6 antisense RNA 1, the group of Antisense RNAs

Basic information

Region (hg38): 7:96955141-97014088

Previous symbols: [ "NCRNA00212" ]

Links

ENSG00000231764 ∙ NCBI:285987 ∙ ∙ HGNC:37151 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the DLX6-AS1 gene.

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the DLX6-AS1 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			53	23	11	87
Total	0	0	53	23	11

Variants in DLX6-AS1

This is a list of pathogenic ClinVar variants found in the DLX6-AS1 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
7-97006014-G-A		not specified	Uncertain significance (Sep 25, 2023)
7-97006025-G-T			Likely benign (Feb 01, 2024)
7-97006028-C-T			Benign (Jul 30, 2024)
7-97006051-GGCA-G			Benign (Sep 06, 2024)
7-97006051-GGCAGCA-G		DLX6-related disorder	Uncertain significance (Nov 19, 2024)
7-97006051-GGCAGCAGCA-G			Uncertain significance (Mar 02, 2023)
7-97006051-GGCAGCAGCAGCA-G			Uncertain significance (Mar 11, 2024)
7-97006051-G-GGCA		DLX6-related disorder	Uncertain significance (May 17, 2024)
7-97006051-G-GGCAGCA			Uncertain significance (Oct 09, 2024)
7-97006051-G-GGCAGCAGCA			Uncertain significance (Dec 09, 2024)
7-97006051-G-GGCAGCAGCAGCA		DLX6-related disorder	Uncertain significance (Sep 21, 2023)
7-97006051-G-GGCAGCAGCAGCAGCA			Uncertain significance (Jul 15, 2022)
7-97006052-GCAGCAGCAGCAGCAGCAGCAGCAA-G			Uncertain significance (Jun 18, 2022)
7-97006052-G-GCAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAA			Uncertain significance (Jul 14, 2023)
7-97006052-G-GCAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAA			Uncertain significance (Aug 31, 2024)
7-97006052-G-GCAGCAGCAGCAGCAGCAGCAGCAA		not specified	Conflicting classifications of pathogenicity (Jan 06, 2025)
7-97006055-GCAGCAGCAGCAGCAGCAGCAA-G			Uncertain significance (Sep 05, 2023)
7-97006055-G-GCAGCAGCAGCAGCAGCAGCAA			Uncertain significance (Nov 30, 2022)
7-97006058-GCAGCAGCAGCAGCAGCAA-G			Uncertain significance (Aug 04, 2023)
7-97006058-G-GCAGCAGCAGCAA			Uncertain significance (Jul 22, 2024)
7-97006061-G-T			Uncertain significance (Jan 06, 2025)
7-97006061-GCAGCAGCAGCAGCAA-G			Uncertain significance (Aug 17, 2023)
7-97006064-G-GCAGCAGCAGCAA			Uncertain significance (Jun 22, 2023)
7-97006066-A-G			Uncertain significance (Mar 18, 2024)
7-97006070-G-A		DLX6-related disorder	Likely benign (Dec 08, 2021)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP

Mouse Genome Informatics

• Gene name: Dlx6os1
• Phenotype: nervous system phenotype (the observable morphological and physiological characteristics of the extensive, intricate network of electochemical structures in the body that is comprised of the brain, spinal cord, nerves, ganglia and parts of the receptor organs that are manifested through development and lifespan)