DLX6-AS1

DLX6 antisense RNA 1, the group of Antisense RNAs

Basic information

Region (hg38): 7:96955141-97014088

Previous symbols: [ "NCRNA00212" ]

Links

ENSG00000231764 ∙ NCBI:285987 ∙ ∙ HGNC:37151 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the DLX6-AS1 gene.

• not provided (48 variants)
• Inborn genetic diseases (4 variants)
• not specified (1 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the DLX6-AS1 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			29	12	11	52
Total	0	0	29	12	11

Variants in DLX6-AS1

This is a list of pathogenic ClinVar variants found in the DLX6-AS1 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
7-97006014-G-A		not specified	Uncertain significance (Sep 25, 2023)
7-97006028-C-T			Benign (Nov 14, 2023)
7-97006051-GGCA-G			Benign (Mar 24, 2021)
7-97006051-GGCAGCA-G		DLX6-related disorder	Uncertain significance (Apr 10, 2023)
7-97006051-GGCAGCAGCA-G			Uncertain significance (Mar 02, 2023)
7-97006051-G-GGCA		DLX6-related disorder	Uncertain significance (Aug 07, 2023)
7-97006051-G-GGCAGCA			Uncertain significance (Aug 17, 2023)
7-97006051-G-GGCAGCAGCAGCA		DLX6-related disorder	Uncertain significance (Sep 21, 2023)
7-97006051-G-GGCAGCAGCAGCAGCA			Uncertain significance (Jul 15, 2022)
7-97006052-GCAGCAGCAGCAGCAGCAGCAGCAA-G			Uncertain significance (Jun 18, 2022)
7-97006052-G-GCAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAGCAGCAGCAGCAGCAA			Uncertain significance (Jul 14, 2023)
7-97006052-G-GCAGCAGCAGCAGCAGCAGCAGCAA		not specified	Conflicting classifications of pathogenicity (Dec 06, 2023)
7-97006055-GCAGCAGCAGCAGCAGCAGCAA-G			Uncertain significance (Sep 05, 2023)
7-97006055-G-GCAGCAGCAGCAGCAGCAGCAA			Uncertain significance (Nov 30, 2022)
7-97006058-GCAGCAGCAGCAGCAGCAA-G			Uncertain significance (Aug 04, 2023)
7-97006061-GCAGCAGCAGCAGCAA-G			Uncertain significance (Aug 17, 2023)
7-97006064-G-GCAGCAGCAGCAA			Uncertain significance (Jun 22, 2023)
7-97006070-G-A		DLX6-related disorder	Likely benign (Dec 08, 2021)
7-97006076-A-G			Likely benign (Apr 10, 2023)
7-97006076-A-ACAG		DLX6-related disorder	Uncertain significance (Apr 09, 2023)
7-97006076-A-ACAGCAGCAG			Uncertain significance (Aug 03, 2023)
7-97006079-G-A			Likely benign (Mar 01, 2023)
7-97006080-C-G			Uncertain significance (Nov 15, 2023)
7-97006081-AGCAGCAGCAGCAGCAGCAACAGCAACA-C			Uncertain significance (Dec 08, 2021)
7-97006082-G-A			Likely benign (Dec 07, 2023)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP

Mouse Genome Informatics

• Gene name: Dlx6os1
• Phenotype: nervous system phenotype (the observable morphological and physiological characteristics of the extensive, intricate network of electochemical structures in the body that is comprised of the brain, spinal cord, nerves, ganglia and parts of the receptor organs that are manifested through development and lifespan)