MIR6886

microRNA 6886, the group of MicroRNAs

Basic information

Region (hg38): 19:11113474-11113534

Links

ENSG00000284553 ∙ NCBI:102465534 ∙ ∙ HGNC:50121 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the MIR6886 gene.

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the MIR6886 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding						0
Total	0	0	0	0	0

Variants in MIR6886

This is a list of pathogenic ClinVar variants found in the MIR6886 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
19-11113481-C-T		Hypercholesterolemia, familial, 1 • Familial hypercholesterolemia	Benign (Jan 15, 2024)
19-11113504-G-A		Hypercholesterolemia, familial, 1 • Familial hypercholesterolemia	Likely benign (Dec 01, 2020)
19-11113504-G-C		Hypercholesterolemia, familial, 1	Likely benign (Jul 19, 2023)
19-11113504-GCGCTGATG-CGGCT		Hypercholesterolemia, familial, 1 • Familial hypercholesterolemia • Cardiovascular phenotype	Uncertain significance (Mar 20, 2023)
19-11113505-C-A		Familial hypercholesterolemia	Uncertain significance (Nov 03, 2023)
19-11113505-C-G		Hypercholesterolemia, familial, 1	Uncertain significance (Jul 19, 2023)
19-11113505-C-T		Hypercholesterolemia, familial, 1 • not specified • Familial hypercholesterolemia • Cardiovascular phenotype	Benign (Jun 10, 2021)
19-11113506-G-A		Hypercholesterolemia, familial, 1 • Familial hypercholesterolemia	Likely benign (Dec 01, 2020)
19-11113506-G-C		Familial hypercholesterolemia • Hypercholesterolemia, familial, 1	Likely benign (Oct 02, 2023)
19-11113507-C-A		Hypercholesterolemia, familial, 1	Likely benign (Jul 10, 2023)
19-11113506-G-GCTGATGCCCTTCTCTCCTCCTGCCT		Hypercholesterolemia, familial, 1	Uncertain significance (Jun 26, 2023)
19-11113508-T-G		Hypercholesterolemia, familial, 1	Uncertain significance (Mar 01, 2016)
19-11113508-TGATG-T		Familial hypercholesterolemia • Hypercholesterolemia, familial, 1	Uncertain significance (Jul 19, 2023)
19-11113509-G-A		Familial hypercholesterolemia	Likely benign (Sep 30, 2019)
19-11113510-A-G		Hypercholesterolemia, familial, 1	Pathogenic (Mar 30, 2017)
19-11113515-C-T		Familial hypercholesterolemia	Likely benign (Mar 21, 2023)
19-11113519-TCTC-T		Hypercholesterolemia, familial, 1	Uncertain significance (Jun 08, 2023)
19-11113520-CT-C		Familial hypercholesterolemia	Uncertain significance (May 06, 2022)
19-11113521-T-G		Familial hypercholesterolemia	Likely benign (Jan 31, 2019)
19-11113522-C-A		Familial hypercholesterolemia	Likely benign (Aug 11, 2023)
19-11113522-C-T		not specified • Familial hypercholesterolemia • Cardiovascular phenotype	Likely benign (Jan 31, 2024)
19-11113525-C-T		Familial hypercholesterolemia • Hypercholesterolemia, familial, 1	Likely benign (Jan 07, 2024)
19-11113529-C-A		Familial hypercholesterolemia	Likely benign (Nov 20, 2023)
19-11113529-C-T		Hypercholesterolemia, familial, 1 • Familial hypercholesterolemia	Conflicting classifications of pathogenicity (Dec 01, 2023)
19-11113530-C-G		Hypercholesterolemia, familial, 1 • not specified • Familial hypercholesterolemia • Cardiovascular phenotype	Likely pathogenic (Aug 27, 2022)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP