SNHG16

small nucleolar RNA host gene 16, the group of Small nucleolar RNA non-coding host genes

Basic information

Region (hg38): 17:76557191-76714384

Links

ENSG00000163597 ∙ NCBI:100507246 ∙ ∙ HGNC:44352 ∙ ∙ ∙ GenCC ∙ jax ∙ Sfari ∙ GnomAD ∙ Pubmed ∙ ClinVar

Phenotypes

GenCC

Source: genCC

No genCC data.

ClinVar

This is a list of variants' phenotypes submitted to ClinVar and linked to the SNHG16 gene.

• Inborn genetic diseases (45 variants)
• not provided (2 variants)

Variants pathogenicity by type

Statistics on ClinVar variants can assist in determining whether a specific variant type in the SNHG16 gene is commonly pathogenic or not.

In the table, we include only reliable ClinVar variants with their consequences to MANE Select, Mane Plus Clinical transcripts, or transcripts with TSL equals 1. Click the count to view the source variants.

Warning: slight differences between displayed counts and the number of variants in ClinVar may occur, primarily due to (1) the application of a different transcript and/or consequence by our variant effect predictor or (2) differences in clinical significance: we classify Benign/Likely benign variants as Likely benign and Pathogenic/Likely pathogenic variants as Likely pathogenic.

Variant type	Pathogenic	Likely pathogenic	VUS	Likely benign	Benign	Sum
synonymous						0
missense						0
nonsense						0
start loss						0
frameshift						0
inframe indel						0
splice donor/acceptor (+/-2bp)						0
splice region						0
non coding			45	1	1	47
Total	0	0	45	1	1

Variants in SNHG16

This is a list of pathogenic ClinVar variants found in the SNHG16 region.

You can filter this list by clicking the number of variants in the Variants pathogenicity by type table.

Position	Type	Phenotype	Significance	ClinVar
17-76566115-A-G		not specified	Uncertain significance (Oct 26, 2022)
17-76566130-C-T		not specified	Uncertain significance (Dec 01, 2024)
17-76566175-C-A		not specified	Uncertain significance (Dec 04, 2024)
17-76566175-C-T		not specified	Uncertain significance (Mar 27, 2023)
17-76566226-C-T		not specified	Uncertain significance (Jul 12, 2023)
17-76566245-G-C		not specified	Uncertain significance (Dec 14, 2022)
17-76567466-T-C		not specified	Uncertain significance (Sep 11, 2024)
17-76567505-A-G		not specified	Uncertain significance (Dec 21, 2023)
17-76570592-A-G		not specified	Uncertain significance (Nov 07, 2022)
17-76572644-T-C		not specified	Uncertain significance (Apr 26, 2023)
17-76572731-G-A		not specified	Uncertain significance (Oct 06, 2022)
17-76572747-C-T		not specified	Uncertain significance (Jun 02, 2023)
17-76573217-C-T		not specified	Uncertain significance (Mar 07, 2024)
17-76573249-A-T		not specified	Uncertain significance (Jan 03, 2024)
17-76573256-C-T		not specified	Uncertain significance (Jun 29, 2022)
17-76573268-C-T		not specified	Uncertain significance (May 15, 2024)
17-76573276-C-T		not specified	Uncertain significance (Dec 17, 2023)
17-76573325-T-A		not specified	Uncertain significance (Oct 22, 2021)
17-76574367-T-C		not specified	Uncertain significance (Oct 10, 2023)
17-76574370-T-A		not specified	Uncertain significance (Oct 12, 2021)
17-76574382-C-T		not specified	Likely benign (Dec 05, 2024)
17-76574383-G-C		not specified	Uncertain significance (Dec 01, 2022)
17-76574394-G-A		not specified	Uncertain significance (Jul 26, 2024)
17-76574398-C-T		not specified	Uncertain significance (Feb 26, 2024)
17-76574401-T-G		not specified	Uncertain significance (Dec 14, 2021)

GnomAD

Source: gnomAD

dbNSFP

Source: dbNSFP

Haploinsufficiency Scores

• pHI: 0.563
• ghis: 0.496

Mouse Genome Informatics

• Gene name: 1810032O08Rik