@genebe/alphagenome_avi

AlphaGenome Atlas Variant Impact (AVI) PHRED score

This annotation contains the PHRED-scaled AlphaGenome Variant Impact (AVI) score for the exhaustive precomputed single-nucleotide variants in the AlphaGenome Atlas GRCh38 dataset. AVI is a single score intended to help prioritise variants with predicted molecular impact across coding and non-coding genomic regions.

Only the PHRED score is retained from the supplied AlphaGenome AVI SNV table. The raw score is intentionally omitted.

Citation

AlphaGenome Atlas team. AlphaGenome Atlas: a predictive map of every possible DNA letter change in the human genome. Google DeepMind, 2026. https://deepmind.google/blog/alphagenome-atlas-a-predictive-map-of-every-possible-dna-letter-change-in-the-human-genome/

AlphaGenome: Avsec Ž, Latysheva N, Cheng J, et al. Advancing regulatory variant effect prediction with AlphaGenome. Nature. 2026;649:1206-1218. doi:10.1038/s41586-025-10014-0.