alfa

ALFA database

The Allele Frequency Aggregator (ALFA) database, developed by the National Center for Biotechnology Information (NCBI), provides a powerful resource for researchers by aggregating allele frequency data from over 200,000 subjects across diverse populations. Accessible at https://www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/, ALFA integrates genomic data from unrestricted studies in the NCBI dbGaP database, offering frequency information for approximately 1 billion variants. This includes population-specific allele frequencies, genotype counts, and Hardy-Weinberg equilibrium (HWE) P-values, making it an invaluable tool for annotating genetic variants.

Data comes from https://ftp.ncbi.nih.gov/snp/population_frequency/latest_release/

Build version 20231103111315