gnomad_exomes2_hg38

gnomAD Exomes (Version 2.1.1, hg19)

gnomAD is a public database developed by the Genome Aggregation Database (gnomAD) consortium, aggregating exome sequencing data to provide comprehensive insights into genetic variation across diverse populations. Version 2.1.1, aligned to the hg19 reference genome, contains allele frequency data for genetic variants, aiding research in population genetics, disease association, and precision medicine.

The database prioritizes entries where the FILTER field equals PASS in case of duplicates, selecting the entry with the highest allele frequency (AF) when necessary. It is a critical resource for researchers and clinicians studying the functional impact of genetic variants.

Build Data

This database was built using the script available at https://github.com/genebe-net/annotation-builder-scripts/tree/main/gnomad2.