cosmic-genomescreensmutant-hg38

cosmic-genomescreensmutant-hg38 0.0.1-101

COSMIC, the Catalogue of Somatic Mutations in Cancer, is the world’s largest and most comprehensive resource for exploring somatic mutations in human cancer, hosted at https://cancer.sanger.ac.uk/cosmic by the Wellcome Sanger Institute. It provides an extensive, expertly curated database of somatic mutations across thousands of cancer types, integrating manually curated data on key cancer genes from the Cancer Gene Census with broad genomic annotations from semi-automated pipelines. Users can access detailed mutation profiles, including coding and non-coding variants, gene fusions, copy number changes, and drug resistance mutations, updated quarterly. COSMIC offers intuitive tools like a genome browser, COSMIC-3D for protein structure visualization, and downloadable datasets (e.g., VCF, TSV), making it ideal for annotating genetic variants with functional and clinical insights. Tailored for researchers, it supports cancer genomics studies, target discovery, and precision oncology, with free academic access and commercial licensing options via QIAGEN.